Notice of Intent to Issue NOFO DE-FOA-0003649: Leveraging Domestic Infrastructure and Resources to Unleash Alternative Chemicals, Fuels and Feedstocks
Applications close Apr 26, 2027
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- Agency
- Golden Field Office
- Opportunity number
- DE-FOA-0003648
- Posted
- Oct 13, 2026
- Closes
- Apr 26, 2027
- Cost sharing required
- false
About this opportunity
CMEI intends to issue, on behalf of AFFO, a NOFO titled, “Leveraging Domestic Infrastructure and Resources to Unleash Alternative Chemicals, Fuels, and Feedstocks”. This NOFO will seek applications for financial assistance awards that would support AFFO’s vision to push the frontiers of science and engineering, advance energy addition, and unleash American energy innovation.
The purpose of the potential NOFO is to solicit innovative technologies that harness existing domestic biomass and pipeline resources to expand energy production and distribution. The NOFO will advance multiple alternative fuels and feedstock technology areas to maximize the benefits of these existing resources: the production of liquid intermediate products made from biomass, that are chemically, thermally, and physically stable, and that could be sold as commodities for various end applications, including for further upgrading to renewable fuels and chemicals; production of commodity chemicals and fuels at market prices from alternative feedstocks, leveraging existing refinery assets; and establishing pilot sites for blended hydrogen-natural gas that closely simulate actual gas distribution networks, to improve reliability, scalability, suitability, performance, and durability.
This NOI is for informational purposes only; we are not requesting comments or applications at this time. All information provided here is subject to change. This notice serves to inform interested parties that the DOE may issue a notice of funding opportunity (NOFO). Please be aware that any future NOFO could differ significantly from what is described here, or one may not be issued at all. We will provide a designated channel for questions once a NOFO is officially released. Complete information, including the full Notice of Intent, can be found on the DOE Funding Opportunities website: https://exchange.energy.gov/.
Who can apply
How to apply
- 1Register your organization
Applications are submitted by your institution, not individuals. Make sure your organization has an active SAM.gov registration (with a UEI) and a Grants.gov account with an Authorized Organization Representative.
- 2Read the full notice
Open the official notice for the complete eligibility rules, review criteria, page limits, and required forms. Applications close Apr 26, 2027.
- 3Download the application package
From the Grants.gov opportunity page, download the package (or apply via your agency's system where required) and prepare each component.
- 4Build and submit
Prepare the budget and narrative, route for institutional sign-off, and submit before the deadline: GrantsManager can track every step for you.
Agency contact: Golden Field Office · exchangehelp@hq.doe.gov
Details are pulled from Grants.gov and can change, always confirm against the official notice. GrantsManager isn't affiliated with these agencies.
Resources for applying
All DOE grants and resources- Proposal submission checklist
A pre-submission checklist for research proposals: solicitation review, internal routing, budget, compliance, and sponsor-system steps to hit the deadline cleanly.
- Direct vs. indirect costs
The difference between direct and indirect costs on research grants, with examples of each, the gray areas like administrative salaries, and how indirect costs are calculated from your F&A rate.
- Reading your Notice of Award
The parts of a Notice of Award that determine what you can spend, when, and what needs prior approval, plus the terms that cause disallowed costs if missed.
- Grant Budget Template
A five-year research grant budget in Excel that calculates fringe, the NIH salary cap, the MTDC base, and F&A automatically.
- Budget Justification Template
A free budget justification (budget narrative) template for research grants, organized by the federal R&R budget categories, with example language for personnel, fringe, equipment, travel, other direct costs, subawards, and F&A.
- Grant Letter of Intent Template
A free grant letter of intent (LOI) template with two versions: the short NIH letter of intent requested in many funding opportunities, and a foundation LOI that pitches the project before a full proposal.
- Letter of Support Template for Grant Applications
A free letter of support template for NIH and other research grant applications, with collaborator and consultant versions, what NIH asks letters to include, and how NIH's move to letters of collaboration affects them.
- F&A & MTDC calculator
Build the Modified Total Direct Cost base, apply your F&A rate, and see total direct costs, indirect costs, and the full award total, with the usual MTDC exclusions handled.
- Grant burn rate
Compare the share of a grant spent and encumbered with the share of the award period elapsed, see the average monthly burn, the monthly spend needed to finish on budget, and the projected run-out date.
- DOE PAMS
Department of Energy Office of Science proposal submission.
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